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Now it will take a long time to scale biofuels, but I'm the only one in the world forecasting oil dropping in price to $35 a barrel by 2030. I'll put it on the record: Oil will not be able to compete with cellulosic biofuels. If you do it from food, the food will get so expensive you can't make fuel out of it.

Certain food-based biofuels like biodiesel have always been a bad idea. Others like corn ethanol have served a useful purpose and essentially are obsoleting themselves.

You know, one of the great things about most renewable technologies - not every technology, but many of them - is the jobs have to be local. When you're talking about a power plant and power generation using solar thermal technology, the jobs will be where the plant is.

I'm not a political person. I'm a techie nerd, and I enjoy the techie part. I mean, all my life, I've loved great technology.

The U.S. has fallen well behind Europe in recognizing climate change and the implications of climate change.

There are parts of the country in America, in the Midwest, where wind is a big resource, and we should absolutely use it. But to try and apply it nationally doesn't make sense. There are technologies that will work that are appropriate to certain regions.

Is it 10 years, 20, 50 before we reach that tipping point where climate change becomes irreversible? Nobody can know. There's clearly a probability distribution. We need to ensure this planet, and we need to do it quickly.

Electric cars are coal-powered cars. Their carbon emissions can be worse than gasoline-powered cars.

I do not know what got me interested in technology. What was very clear to me very early on was that I was not interested in religion and that naturally increased my curiosity about science and technology, and I fundamentally believe the two are conflicting.

Religion asks you to believe things without questioning, and technology and science always encourage you to ask hard questions and why it is important in science and technology. So I was always interested in science and technology.

Everybody else is afraid to fail. I do not really care because when I fail, I try something new.

If I collected all the diamonds in the world, I'd have no 'income' but I'd have a lot of 'assets'. Would my company be worth nothing because I have no income? A lot of Net companies are collecting assets. They have to be measured with a new set of metrics.

The only way you multiply resources is with technology. To really affect poverty, energy, health, education, or anything else - there is no other way.

What an entrepreneur does is to build for the long run. If the market is great, you get all of the resources you can. You build to it. But a good entrepreneur is always prepared to throttle back, put on the brakes, and if the world changes, adapt to the world.

I've probably failed more often than anybody else in Silicon Valley. Those don't matter. I don't remember the failures. You remember the big successes.

In my view, it's irreverence, foolish confidence and naivety combined with persistence, open mindedness and a continual ability to learn that created Facebook, Google, Yahoo, eBay, Microsoft, Apple, Juniper, AOL, Sun Microsystems and others.

Seeking an acquisition from the start is more than just bad advice for an entrepreneur. For the entrepreneur it leads to short term tactical decisions rather than company-building decisions and in my view often reduces the probability of success.

Imagine the world of mobile based on Nokia and Motorola if Apple had not been restarted by a missionary entrepreneur named Steve Jobs who cared more for his vision than being tactical and financial.

If everyone played it safe, we wouldn't get anywhere.

I'm a fiscal hawk. I vote against all taxes, but I do believe the environment, and climate change, is a bigger issue than fiscal deficits are as a risk to the nation.

Entrepreneurs have the flexibility and the ability to do things that large companies simply cannot. Could a large company pull off a trick like Amyris, going from anti-malaria medicine to next-generation fuel?

Startups allow technologists and scientists to take risks and change plans in a way that would be frowned upon in a big company. Having said that, big companies will play a key role in certain areas and in partnerships with little companies. Each has its strengths.

Will biofuel usage require land? Absolutely, but we think the ability to use winter cover crops, degraded land, as well as using sources such as organic waste, sewage, and forest waste means that actual land usage will be limited. Just these sources can replace most of our imported oil by 2030 without touching new land.

Knowing whose advice to take and on what topic is the single most important decision an entrepreneur can make.

First, you should take money and have plenty of money fueling your tank. But money becomes dangerous if you assume it's going to keep coming. Make sure you can get your burn rate to a sustainable level if you hit the brakes hard, within 90 days.

Who cares if companies are overvalued or not?

Entrepreneurs can benefit a lot from the right help and advice, and you can avoid costly mistakes. You can get incredible leverage in hiring people who wouldn't even talk to you if you have the right help. An investor isn't about money - it's about the help and advice you can get.

When I started doing things on my own, I was figuring - remember, it was a very nascent market. And there was a lot that was unknown about the renewable marketplace in 2004, early 2003, when I was planning on it.

We love serious technology innovations, and there is a strong bias towards large technology innovations that are sort of disruptive to the current market.

You take something like RingCentral. It doesn't need any more money or financing: it is relatively mature, recurring revenue business - not really worried - but you know, we could sell it tomorrow. We have not been in a rush to sell it. We don't care about exits as much. We care about building fundamental value.

Our focus is not on exit. In fact if you talk to any of my entrepreneurs, I'm generally saying, 'Don't sell the company,' when other investors want to sell. I'd much rather focus on building long-term value in building companies rather than worrying about exits.

I generally disagree with most of the very high margin opportunities. Why? Because it's a business strategy tradeoff: the lower the margin you take, the faster you grow.

The winter period between September and March in this country, when land sits fallow and is subject to topsoil loss, we could be enriching the soil and growing all the biomass we need to replace imported gasoline.

We like to say at Khosla Ventures, and this is one of the reasons to do what we do, we'll take technical risks that nobody else will.

I don't believe - till something radical changes that we are not on track to do - that hybrids are material to climate change. They're fashionable, everybody loves them, the Prius is selling well, but so are Gucci bags. But they don't impact the way the world carries stuff. You know it's a fashion statement.

If you have a carbon cap and trade system, there'd be an agreed-to limit the amount of carbon we emit. That changes the economic picture for fossil technologies and for the renewable technologies. It makes the renewable technologies more attractive and the fossils less attractive.

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