Top 10 Venkatraman Ramakrishnan Quotes

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I knew the ribosome was going to be the focus of Nobel prizes. It stands at the crossroads of biology, between the gene and what comes out of the gene. But I had convinced myself I was not going to be a winner.

I remember reading a 'Scientific American' article about the use of new physical techniques - including neutron scattering - as a method for unravelling the structure of the ribosome. I was fascinated.

It takes a certain amount of courage to tackle very hard problems in science, I now realise. You don't know what the timescale of your work will be: decades or only a few years.

Science today is a highly collaborative exercise, and to convert it into a contest, as the Nobel does, is a bad way to look at science.

I was born in 1952 in Chidambaram, an ancient temple town in Tamil Nadu best known for its temple of Nataraja, the lord of dance.

My mother, R. Rajalakshmi, taught at Annamalai University in Chidambaram, and during the day, I was well cared for by aunts and grandparents in the usual way of an extended Indian family.

Unusually for an Indian man of his generation, my father, being aware of my mother's intellectual abilities, encouraged her to go abroad by herself to obtain a Ph.D.

My childhood and adolescence were filled with visiting scientists from both India and abroad, many of whom would stay with us. A life of science struck me as being both interesting and particularly international in its character.

During the decade following the discovery of the double-helical structure of DNA, the problem of translation - namely, how genetic information is used to synthesize proteins - was a central topic in molecular biology.

I began studying ribosomes as a postdoctoral fellow in Peter Moore's laboratory in 1978.

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