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The really big difference is that what you make with a molecular machine can be completely precise, down to the tiniest degree of detail that can exist in the world.

And that because the moving parts are a million times smaller than the ones we're familiar with, they move a million times faster, just as a smaller tuning fork produces a higher pitch than a large one.

On the molecular scale, you find it's reasonable to have a machine that does a million steps per second, a mechanical system that works at computer speeds.

If you take all the factories in the world today, they could make all the parts necessary to build more factories like themselves. So, in a sense, we have a self-replicating industrial system today, but it would take a tremendous effort to copy what we already have.

The basic parts, the start-up molecules, can be supplied in abundance and don't have to be made by some elaborate process. That immediately makes things simpler.

The other advantage is that in conventional manufacturing processes, it takes a long time for a factory to produce an amount of product equal to its own weight. With molecular machines, the time required would be something more like a minute.

Today we have big, crude instruments guided by intelligent surgeons, and we have little, stupid molecules of drugs that get dumped into the body, diffuse around and interfere with things as best they can. At present, medicine is unable to heal anything.

Any powerful technology can be abused.

My greatest concern is that the emergence of this technology without the appropriate public attention and international controls could lead to an unstable arms race.

I've encountered a lot of people who sound like critics but very few who have substantive criticisms. There is a lot of skepticism, but it seems to be more a matter of inertia than it is of people having some real reason for thinking something else.

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