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A universe that came from nothing in the big bang will disappear into nothing at the big crunch. Its glorious few zillion years of existence not even a memory.

In science, a healthy skepticism is a professional necessity, whereas in religion, having belief without evidence is regarded as a virtue.

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Science, we are repeatedly told, is the most reliable form of knowledge about the world because it is based on testable hypotheses. Religion, by contrast, is based on faith. The term 'doubting Thomas' well illustrates the difference.

When I was a student, the laws of physics were regarded as completely off limits. The job of the scientist, we were told, is to discover the laws and apply them, not inquire into their provenance.

The origin of life is one of the great outstanding mysteries of science.

The language of chemistry simply does not mesh with that of biology. Chemistry is about substances and how they react, whereas biology appeals to concepts such as information and organisation. Informational narratives permeate biology.

The way life manages information involves a logical structure that differs fundamentally from mere complex chemistry. Therefore chemistry alone will not explain life's origin, any more than a study of silicon, copper and plastic will explain how a computer can...

Most research into life's murky origin has been carried out by chemists. They've tried a variety of approaches in their attempts to recreate the first steps on the road to life, but little progress has been made. Perhaps that is...

Cancer is such a ruthless adversary because it behaves as if it has its own fiendishly cunning agenda.

Cancer cells come pre-programmed to execute a well-defined cascade of changes, seemingly designed to facilitate both their enhanced survival and their dissemination through the bloodstream. There is even an air of conspiracy in the way that tumours use chemical signals...

In the frantic search for an elusive 'cure,' few researchers stand back and ask a very basic question: why does cancer exist? What is its place in the grand story of life?

Astonishingly, in spite of decades of research, there is no agreed theory of cancer, no explanation for why, inside almost all healthy cells, there lurks a highly efficient cancer subroutine that can be activated by a variety of agents -...

If we do discover more than one type of life on Earth, we can be fairly certain that the universe is teeming with it, for it would be inconceivable that life started twice here but never on all the other...

The vast majority of terrestrial species are in fact microbes, and scientists have only begun scratching the surface of the microbial realm. It is entirely possible that examples of life as we don't know it have so far been overlooked.

No planet is more earth-like than Earth itself, so if life really does pop up readily in earth-like conditions, then surely it should have arisen many times right here on our home planet? And how do we know it didn't?...

Scientists have no agreed theory of the origin of life - plenty of scenarios, conjectures and just-so stories, but nothing with solid experimental support.

Astronauts have been stuck in low-Earth orbit, boldly going nowhere. American attempts to kick-start a new phase of lunar exploration have stalled amid the realisation that NASA's budget is too small for the job.

Clearly, some creative thinking is badly needed if humans are to have a future beyond Earth. Returning to the Moon may be worthy and attainable, but it fails to capture the public's imagination. What does get people excited is the...

A permanent base on Mars would have a number of advantages beyond being a bonanza for planetary science and geology. If, as some evidence suggests, exotic micro-organisms have arisen independently of terrestrial life, studying them could revolutionise biology, medicine and...

Perhaps the best motivation for going to Mars is political. It is obvious that no single nation currently has either the will or the resources to do it alone, but a consortium of nations and space agencies could achieve it...

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