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The earliest sensation at the onset of illness, often preceding the recognition of identifiable symptoms, is apprehension. Something has gone wrong, and a glimpse of mortality shifts somewhere deep in the mind. It is the most ancient of our fears.

Medical knowledge and technical savvy are biodegradable. The sort of medicine that was practiced in Boston or New York or Atlanta fifty years ago would be as strange to a medical student or intern today as the ceremonial dance of...

The dilemma of modern medicine, and the underlying central flaw in medical education and, most of all, in the training of interns, is the irresistible drive to do something, anything. It is expected by patients and too often agreed to...

The most solid piece of scientific truth I know of is that we are profoundly ignorant about nature.

As a species, taking all in all, we are still too young, too juvenile, to be trusted. We have spread across the face of the earth in just a few thousand years, no time at all as evolution clocks time,...

Of all celestial bodies within reach or view, as far as we can see, out to the edge, the most wonderful and marvellous and mysterious is turning out to be our own planet earth. There is nothing to match it...

We are not like the social insects. They have only the one way of doing things and they will do it forever, coded for that way. We are coded differently, not just for binary choices, go or no-go. We can...

At this early stage in our evolution, now through our infancy and into our childhood and then, with luck, our growing up, what our species needs most of all, right now, is simply a future.

Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us.

It is only when you watch the dense mass of thousands of ants, crowded together around the Hill, blackening the ground, that you begin to see the whole beast, and now you observe it thinking, planning, calculating. It is an...

The future is too interesting and dangerous to be entrusted to any predictable, reliable agency. We need all the fallibility we can get. Most of all, we need to preserve the absolute unpredictability and total improbability of our connected minds....

Survival, in the cool economics of biology, means simply the persistence of one's own genes in the generations to follow.

A multitude of bees can tell the time of day, calculate the geometry of the sun's position, argue about the best location for the next swarm. Bees do a lot of close observing of other bees; maybe they know what...

Animals have genes for altruism, and those genes have been selected in the evolution of many creatures because of the advantage they confer for the continuing survival of the species.

We are not made up, as we had always supposed, of successively enriched packets of our own parts. We are shared, rented, occupied. At the interior of our cells, driving them, providing the oxidative energy that sends us out for...

The uniformity of the earth's life, more astonishing than its diversity, is accountable by the high probability that we derived, originally, from some single cell, fertilized in a bolt of lightning as the earth cooled.

We live in a dancing matrix of viruses; they dart, rather like bees, from organism to organism, from plant to insect to mammal to me and back again, and into the sea, tugging along pieces of this genome, strings of...

The need to make music, and to listen to it, is universally expressed by human beings. I cannot imagine, even in our most primitive times, the emergence of talented painters to make cave paintings without there having been, near at...

In the fields I know best, among the life sciences, it is required that the most expert and sophisticated minds be capable of changing course - often with a great lurch - every few years.

I suggest that the introductory courses in science, at all levels from grade school through college, be radically revised. Leave the fundamentals, the so-called basics, aside for a while, and concentrate the attention of all students on the things that...

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